| Description | NH-bis(PEG3-azide) is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules. |
| In vitro | PROTACs 通过连接器连接两种不同的配体；一个是 E3 泛素连接酶的配体，另一个是目标蛋白的配体。PROTACs 利用细胞内的泛素-蛋白酶体系统，有选择性地降解目标蛋白质。[1] |
| molecular weight | 419.48 |
| Molecular formula | C16H33N7O6 |
| CAS | 1258939-39-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| References | 1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |