| Description | 1. Alisol B 23-acetate (Alisol B Acetate) produces protective effect against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes. 2. Alisol B 23-acetate produces promotive effect on liver regeneration, due to FXR-mediated regulation of genes involved in hepatocyte proliferation and hepato-protection. 3. Alisol B 23-acetate produces a protective effect against CCl4-induced hepatotoxicity, due to FXR and STAT3-mediated gene regulation. |
| Synonyms | Alisol B Acetate, Alisol B monoacetate, 23-O-Acetylalisol B, 23-Acetylalismol B, 泽泻醇B乙酸酯 |
| molecular weight | 514.74 |
| Molecular formula | C32H50O5 |
| CAS | 26575-95-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 60 mg/mL (116.56 mM) |
| References | 1. Wang C , Zhang J X , Shen X L , et al. Reversal of P-glycoprotein-mediated multidrug resistance by Alisol B 23-acetate[J]. Biochemical Pharmacology, 2004, 68(5):843-855. |