| Description | Neurokinin A(4-10) TFA(97559-35-8 free base) is a tachykinin NK2 receptor agonist[1]. |
| In vitro | Neurokinin A (NKA) 及其缩短形式 NKA(4-10) 是人类结肠环形肌的强效痉挛素，这一作用仅通过促胆碱能NK2受体介导。对 Neurokinin A (NKA) 片段 NKA(4-10) 进行了结构-活性研究，以探讨氨基酸残基对人类结肠环形肌中NK2受体的效力、潜力和亲和力的重要性。通过体外自放射成像和放射配体结合[1]，已在该组织中证明 NK2 受体的高密度。 |
| Synonyms | Neurokinin A(4-10) TFA |
| molecular weight | 880.93 |
| Molecular formula | C36H55F3N8O12S |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: < 0.1 mg/mL (insoluble) |
| References | 1. Warner FJ, et al. Structure-activity relationship of neurokinin A(4-10) at the human tachykinin NK(2) receptor: the effect of amino acid substitutions on receptor affinity and function. Biochem Pharmacol. 2002 Jun 15;63(12):2181-6. |