| Description | Nanchangmycin (Nanchangmycin A), a polyether antibiotic, is similar to the structure of dianemycin. It is very potent against the broad spectrum of harmful nematodes and insects but not for mammals and plants. |
| In vitro | Nanchangmycin对抗革兰氏阳性细菌。 |
| In vivo | Nanchangmycin，作为家禽生长促进剂，有效治疗鸡的球虫病。作为一种细菌来源的天然产物，Nanchangmycin在多种细胞类型中强效阻断ZIKV和DENV感染。 |
| Cell experiments | 5×10E3 U2OS cells were plated in 25ul media per well in 384-well plates and cultured for 24 hours. Add 50 nl of Nanchangmycin, which is 0.7uM dissolved in 0.2% DMSO, to each well incubating for 1 hour. |
| Synonyms | Nanchangmycin A, 南昌霉素 |
| molecular weight | 889.1 |
| Molecular formula | C47H77NaO14 |
| CAS | 65101-87-3 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: < 1 mg/mL (insoluble or slightly soluble) DMSO: 88.9 mg/mL (100 mM) |
| References | 1. Liu T, et al. Chem Biol. 2008, 15(5), 449-458. |