| Description | Mps1-IN-6 is a potent Mps1 inhibitor that demonstrates antiproliferative and antitumor activities, exhibiting an IC50 of 2.596 nM [1]. |
| In vitro | Mps1-IN-6（化合物31）（0-10 µM；72小时）展现出抗增殖作用，其针对MDA-MB-468、MCF-7、REB、MV4-11、HT-29细胞系的IC 50 值依次为0.221、>10、>10、0.823、>10 µM [1]。 |
| In vivo | Mps1-IN-6以30和60 mg/kg剂量，通过静脉注射(iv.)方式，每天一次连续21天给药，展现了在小鼠体内的抗肿瘤活性[1]。 |
| molecular weight | 633.74 |
| Molecular formula | C35H39N9O3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |