| Description | ML303 is an antagonist of pyrazolopyridine influenza virus nonstructural protein 1 (NS1) (IC90 : 155 nM). |
| In vitro | 在MDCK细胞中，ML303处理恢复了IFN-β mRNA水平[1]。 |
| Target activity | H1N1:EC50: 0.7 μM |
| molecular weight | 399.37 |
| Molecular formula | C21H16F3N3O2 |
| CAS | 1638211-04-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 3.99 mg/mL (10 mM) |
| References | 1. Patnaik S, et al. Identification, design and synthesis of novel pyrazolopyridine influenza virus nonstructural protein 1 antagonists. Bioorg Med Chem Lett. 2019 May 1;29(9):1113-1119. |