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MK-3697

CAS No.: 1224846-01-8

MK-3697, an isonicotinamide small molecule, acts as a potent and selective Orexin 2 receptor antagonist (Ki: 0.95 nM).
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Description MK-3697, an isonicotinamide small molecule, acts as a potent and selective Orexin 2 receptor antagonist (Ki: 0.95 nM).
Target activity OX2:0.95 nM(ki)
molecular weight 447.51
Molecular formula C23H21N5O3S
CAS 1224846-01-8
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 55 mg/mL (122.9 mM)
References 1. Anthony J. Roecker, et al. Bioorganic & Medicinal Chemistry Letters Available online 26 August 2014.