| Description | MEN 10207 acetate is a selective antagonist for NK-2 tachykinin receptor. |
| In vivo | 脊髓内注射神经激肽A和物质P以相似方式促进屈肌反射。对于脊髓内注射的神经激肽A（而非物质P），通过预先处理Men 10207醋酸盐[2]可以剂量依赖性地阻断反射的促进作用。 |
| molecular weight | 1169.29 |
| Molecular formula | C59H72N14O12 |
| Storage | keep away from moisture|Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Rovero P, Astolfi M, Renzetti AR, Patacchini R, Giachetti A, Maggi CA. Role of D-tryptophan for affinity of MEN 10207 tachykinin antagonist at NK2 receptors. Peptides. 1991 Sep-Oct;12(5):1015-8. doi: 10.1016/0196-9781(91)90053-r. PMID: 1666180. 2. Xu XJ, Maggi CA, Wiesenfeld-Hallin Z. On the role of NK-2 tachykinin receptors in the mediation of spinal reflex excitability in the rat. Neuroscience. 1991;44(2):483-90. |