| Description | MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence. MAO-B-IN-9 has neuroprotective effects against Aβ1-42-induced neuronal cell death, which may be related to the anti-aggregation effect of Aβ1-42. |
| Target activity | MAO-B:0.178 ± 0. μM |
| molecular weight | 300.4 |
| Molecular formula | C18H24N2O2 |
| CAS | 2416910-88-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 12 mg/mL (39.95 mM) |
| References | 1. Košak U, et al. N-alkylpiperidine carbamates as potential anti-Alzheimer's agents. Eur J Med Chem. 2020 ; 197:112282. |