| Description | L-689502 is a potent HIV-l protease inhibitor (IC50: 1 nM). |
| In vitro | L694746 is as potent as L-689502 in inhibiting the HIV-l protease despite being structurally different from L-689502. Both L694746 and L-689502 inhibit HIV-l protease activity in a concentration-dependent manner. Pepstatin is much less potent than either compound (IC50: 2 μM) [1]. |
| Target activity | HIV-l protease:1 nM |
| molecular weight | 673.84 |
| Molecular formula | C39H51N3O7 |
| CAS | 138483-63-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Lingham RB, et al. HIV-1 protease inhibitory activity of L-694,746, a novel metabolite of L-689,502. Biochem Biophys Res Commun. 1991 Dec 31;181(3):1456-61. |