| Description | MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a Ki of 696 nM, making it suitable for Alzheimer's disease research [1]. |
| In vitro | MAO-B-IN-3（1 μM）对MAO-A的抑制率仅为3%。在稳定表达h5-HT6R的HEK293细胞系中，该化合物对5-HT6R具有强竞争性结合力，K i 值达到696 nM [1]。 |
| Target activity | MAO-B:96 nM, 5-HT6 receptor (human):696 nM (Ki) |
| molecular weight | 387.47 |
| Molecular formula | C24H25N3O2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |