| Description | Malvidin chloride has anti-spermatogenic, and antioxidant activities. It can prevent endothelial dysfunction by inhibiting ROS and XO-1. |
| In vitro | HUVECs were in vitro cultured in the presence of Mv-Cl(1, 5 and 10 μmol/L), angiotensinⅡ(Ang II, 10-2 μmol/L) and their combination, respectively. DMSO was used as control. The ROS content in the cells was detected by immunofluorescence. The soluble XO-1 protein content in the cell culture supernatant was detected by ELISA. The protein expression of XO-1 in the cells was assessed by Western blotting. The content of ROS and the protein expression of XO-1 in HUVECs were decreased when treated with low concentration of Mv-Cl. Ang II significantly increased ROS and XO-1 content, and Mv-Cl appeared to specifically down-regulate the production of ROS and XO-1[1] |
| molecular weight | 366.75 |
| Molecular formula | C17H15ClO7 |
| CAS | 643-84-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Antioxidant Effect of Blueberry Malvidin Chloride in Human Umbilical Vein Endothelial Cells.Food Science, 2015. |