| Description | MAC13772 is a potent inhibitor of the enzyme BioA with an IC50 of 250 nM thereby inhibiting biotin biosynthesis. MAC13772 exhibits antibacterial activity. |
| Target activity | BioA:250 nM |
| molecular weight | 227.24 |
| Molecular formula | C8H9N3O3S |
| CAS | 4871-40-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 15 mg/mL (66.01 mM), Sonication is recommended. |
| References | 1. Zlitni S, et al. Metabolic suppression identifies new antibacterial inhibitors under nutrient limitation. Nat Chem Biol. 2013 Dec;9(12):796-804. |