| Description | LY 163443 is an dual receptor antagonist of LTD4 and LTE4. |
| Synonyms | LY163443, LY-163443 |
| molecular weight | 366.41 |
| Molecular formula | C20H22N4O3 |
| CAS | 97581-70-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Lawrence JW, Kroll DJ, Eacho PI. Ligand-dependent interaction of hepatic fatty acid-binding protein with the nucleus. J Lipid Res. 2000 Sep;41(9):1390-401. PubMed PMID: 10974046. 2. Nuessler V, Pelka-Fleischer R, Zwierzina H, Wilmanns W, Denzlinger C. Effects of progesterone and leukotriene receptor antagonists in experimental models of P-glycoprotein-related resistance. Eur J Med Res. 1997 Apr 21;2(4):159-64. PubMed PMID: 9110922. 3. Eacho PI, Foxworthy PS, Lawrence JW, Herron DK, Noonan DJ. Common structural requirements for peroxisome proliferation by tetrazole and carboxylic acid-containing compounds. Ann N Y Acad Sci. 1996 Dec 27;804:387-402. PubMed PMID: 8993558. 4. Dillard RD, Hahn RA, McCullough D, Carr FP, Rinkema LE, Roman CR, Fleisch JH. (Phenylmethoxy)phenyl derivatives of omega-oxo- and omega-tetrazolylalkanoic acids and related tetrazoles. Synthesis and evaluation as leukotriene D4 receptor antagonists. J Med Chem. 1991 Sep;34(9):2768-78. PubMed PMID: 1654427. |