| Description | Dexecadotril is a powerful and selective neprilysin inhibitor. It behaves as a prodrug of the enantiomer of thiorphan. |
| Synonyms | Retorphan |
| molecular weight | 385.48 |
| Molecular formula | C21H23NO4S |
| CAS | 112573-72-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Monteil T, Danvy D, Sihel M, Leroux R, Plaquevent JC. Strategies for access to enantiomerically pure ecadotril, dexecadotril and fasidotril: a review. Mini Rev Med Chem. 2002 Jun;2(3):209-17. Review. PubMed PMID: 12370063. 2. James N, Ramanathan K. Discovery of Potent ALK Inhibitors Using Pharmacophore-Informatics Strategy. Cell Biochem Biophys. 2018 Jun;76(1-2):111-124. doi: 10.1007/s12013-017-0800-y. Epub 2017 May 6. PubMed PMID: 28477056. |