| Description | LRE1 is a specific and allosteric soluble adenylyl cyclase inhibitor. |
| In vitro | LRE1通过独特的异构体机制，抑制可溶性腺苷酸环化酶(sAC)的活性，其作用机制是结合到碳酸氢盐激活位点，从而阻止sAC依赖的细胞和生理过程，促进对sAC抑制治疗潜力的探索[1]。 |
| molecular weight | 280.78 |
| Molecular formula | C12H13ClN4S |
| CAS | 1252362-53-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 112.5 mg/mL (400.7 mM), Sonication is recommended. |
| References | 1. os-Espiritu L, et al. Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase. Nat Chem Biol. 2016 Oct;12(10):838-44. |