| Description | LEQ506, also known as NPV-LEQ506, is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity. Smoothened antagonist LEQ506 selectively binds to the Hedgehog (Hh)-ligand cell surface receptor Smo, which may result in the suppression of the Hh signaling pathway, thereby inhibiting tumor cell growth. |
| molecular weight | 439.55 |
| Molecular formula | C27H29N5O |
| CAS | 1057677-92-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |