PeptideDB

LBT 999

CAS No.: 877467-20-4

LBT 999 is used as a dopamine reuptake inhibitor.
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This product is for research use only, not for human use. We do not sell to patients.

Description LBT 999 is used as a dopamine reuptake inhibitor.
Synonyms LBT999, LBT-999
molecular weight 331.42
Molecular formula C20H26FNO2
CAS 877467-20-4
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Sérrière S, Tauber C, Vercouillie J, Guilloteau D, Deloye JB, Garreau L, Galineau L, Chalon S. In vivo PET quantification of the dopamine transporter in rat brain with [¹⁸F]LBT-999. Nucl Med Biol. 2014 Jan;41(1):106-13. doi: 10.1016/j.nucmedbio.2013.09.007. Epub 2013 Oct 8. PubMed PMID: 24210285. 2. Saba W, Peyronneau MA, Dollé F, Goutal S, Bottlaender M, Valette H. Difficulties in dopamine transporter radioligand PET analysis: the example of LBT-999 using [18F] and [11C] labelling Part I: PET studies. Nucl Med Biol. 2012 Feb;39(2):227-33. doi: 10.1016/j.nucmedbio.2011.08.003. Epub 2011 Oct 26. PubMed PMID: 22033025. 3. Peyronneau MA, Saba W, Dollé F, Goutal S, Coulon C, Bottlaender M, Valette H. Difficulties in dopamine transporter radioligand PET analysis: the example of LBT-999 using [18F] and [11C] labelling: part II: Metabolism studies. Nucl Med Biol. 2012 Apr;39(3):347-59. doi: 10.1016/j.nucmedbio.2011.09.006. Epub 2011 Dec 11. PubMed PMID: 22154687. 4. Dollé F, Emond P, Mavel S, Demphel S, Hinnen F, Mincheva Z, Saba W, Valette H, Chalon S, Halldin C, Helfenbein J, Legaillard J, Madelmont JC, Deloye JB, Bottlaender M, Guilloteau D. Synthesis, radiosynthesis and in vivo preliminary evaluation of [11C]LBT-999, a selective radioligand for the visualisation of the dopamine transporter with PET. Bioorg Med Chem. 2006 Feb 15;14(4):1115-25. Epub 2005 Oct 10. PubMed PMID: 16219467.