PeptideDB

LASSBio-1359

CAS No.: 1396397-19-5

LASSBio-1359 is an adenosine receptor agonist. It acts by inducing relaxation of the corpus cavernosum. It also acts as
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Description LASSBio-1359 is an adenosine receptor agonist. It acts by inducing relaxation of the corpus cavernosum. It also acts as a novel selective phosphodiesterase.
Synonyms LASSBio1359, LASSBio 1359
molecular weight 298.34
Molecular formula C17H18N2O3
CAS 1396397-19-5
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
References 1. Montes GC, Hammes N, da Rocha MD, Montagnoli TL, Fraga CA, Barreiro EJ, Sudo RT, Zapata-Sudo G. Treatment with Adenosine Receptor Agonist Ameliorates Pain Induced by Acute and Chronic Inflammation. J Pharmacol Exp Ther. 2016 Aug;358(2):315-23. doi: 10.1124/jpet.115.231241. Epub 2016 May 18. PubMed PMID: 27194479. 2. Moura VJ, Alencar AK, Calasans-Maia Jde A, da Silva JS, Fraga CA, Zapata-Sudo G, Barreiro EJ, Sudo RT. Novel agonist of adenosine receptor induces relaxation of corpus cavernosum in guinea pigs: an in vitro and in vivo study. Urology. 2015 May;85(5):1214.e17-21. doi: 10.1016/j.urology.2015.02.006. PubMed PMID: 25917739. 3. Alencar AK, Pereira SL, Montagnoli TL, Maia RC, Kümmerle AE, Landgraf SS, Caruso-Neves C, Ferraz EB, Tesch R, Nascimento JH, de Sant'Anna CM, Fraga CA, Barreiro EJ, Sudo RT, Zapata-Sudo G. Beneficial effects of a novel agonist of the adenosine A2A receptor on monocrotaline-induced pulmonary hypertension in rats. Br J Pharmacol. 2013 Jul;169(5):953-62. doi: 10.1111/bph.12193. PubMed PMID: 23530610; PubMed Central PMCID: PMC3696320.