| Description | L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride) is a fatty acid metabolite with antithrombotic properties that protects mice from ischemic stroke by counteracting intracerebral thrombosis in the tMCAO model.L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride) is a fatty acid metabolite with antithrombotic properties. Palmitoylcarnitine chloride inhibits the Na/K pump in the heart and inhibits FeCl 3-induced arterial thrombosis Attenuates intracerebral thrombosis and inflammation in a mouse model of transient middle cerebral artery occlusion (tMCAO). |
| In vitro | L-Palmitoylcarnitine chloride（1-20μM）以剂量依赖性方式抑制乙酰胆碱和P物质诱导的内皮依赖性松弛，而对静息张力和硝酸甘油诱导的松弛没有影响[1]。 |
| In vivo | 在体内，L-Palmitoylcarnitine chloride 可增加大鼠肠道对抗生素头孢西丁的吸收。 |
| Synonyms | Palmitoyl-L-carnitine chloride |
| molecular weight | 436.07 |
| Molecular formula | C23H46ClNO4 |
| CAS | 18877-64-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | H2O: Slightly soluble, Sonication and heating are recommended. |
| References | 1. Inoue N, et al. Palmitoyl-L-carnitine modifies the function of vascular endothelium. Cardiovasc Res. 1994 Jan;28(1):129-34. 2. Haruna T, et al. Alteration of the membrane lipid environment by L-palmitoylcarnitine modulates K(ATP) channels in guinea-pig ventricular myocytes. Pflugers Arch. 2000;441(2-3):200-207. |