| Description | L-Leucine-1-13C (L-Leucine-13C) is a 13C-labeled L-Leucine that significantly enhances the affinity of GLP-4. |
| Synonyms | L-(1-13C)Leucine, (1-13C)Leucine |
| molecular weight | 132.17 |
| Molecular formula | C6CH13NO2 |
| CAS | 74292-94-7 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: < 1 mg/mL (insoluble） H2O: 2 mg/mL (15.13 mM), Sonication is recommended. |
| References | 1. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. 2. Baoshan Xu, et al. Stimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome. PLoS Genet. 2013;9(10):e1003857. 3. Bruckbauer A, et al. Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice. Nutr Metab (Lond). 2012 Aug 22;9(1):77. 4. Rachdi L, et al. L-leucine alters pancreatic β-cell differentiation and function via the mTor signaling pathway. Diabetes. 2012 Feb;61(2):409-17. |