| Description | KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo. |
| Synonyms | KRP-199 sodium(221164-28-9 Free base) |
| molecular weight | 561.33 |
| Molecular formula | C22H12F3N5Na2O7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 1 mg/mL, Sonication is recommended. |
| References | 1. Yasuo Takano,et al.Synthesis and AMPA receptor antagonistic activity of a novel 7-imidazolyl-6-trifluoromethyl quinoxalinecarboxylic acid with a substituted phenyl group and improved its good physicochemical properties by introduced CF3 group,Bioorganic & Medicinal Chemistry Letters,Volume 14, Issue 20,2004,Pages 5107-5111,ISSN 0960-894X. 2. Takano Y,et al. Design and synthesis of novel 7-heterocycle-6-trifluoromethyl-3-oxoquinoxaline-2-carboxylic acids bearing a substituted phenyl group as superior AMPA receptor antagonists with good physicochemical properties. Bioorg Med Chem. 2006 Feb 1;14(3):776-92. |