| Description | KM02894 is a glutamate release inhibitor. Cancer cells release high levels of glutamate that can disrupt normal bone turnover, which can lead to cancer-induced bone pain.KM02894 may be used in the study of tumor-related diseases. |
| molecular weight | 215.3 |
| Molecular formula | C7H9N3OS2 |
| CAS | 116850-74-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 30.0 mg/mL (139.3 mM), Sonication and heating to 60℃ are recommended. |
| References | 1. Fazzari J, et al. Inhibitors of glutamate release from breast cancer cells; new targets for cancer-induced bone-pain. Sci Rep. 2015;5:8380. |