| Description | KHK-IN-2 is a selective inhibitor of ketohexokinase with an IC50 value of 0.45 μM. |
| Target activity | KHK:0.45 μM |
| molecular weight | 372.34 |
| Molecular formula | C16H19F3N4O3 |
| CAS | 2135304-43-5 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 200 mg/mL (537.1 mM), Sonication is recommended. |
| References | 1. Huard K, et al. Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK). J Med Chem. 2017 Sep 28;60(18):7835-7849. |