| Description | (+)-KCC2 blocker 1 is a selective blocker of KCC2 (IC50 = 0.4 μM). |
| In vitro | (+)-KCC2 blocker 1是KCC2 blocker 1的对映体，相较于(-)-KCC2 blocker 1，其效力有100倍的差异[1]。 |
| Target activity | KCC2:0.4 μM |
| molecular weight | 415.5 |
| Molecular formula | C22H25NO5S |
| CAS | 1228439-71-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (120.34 mM) |
| References | 1. Pégurier C, et al. Benzyl prolinate derivatives as novel selective KCC2 blockers. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2542-5. |