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Arnidiol

CAS No.: 6750-30-7

Arnidiol is a pentacyclic triterpene isolated from Barleria Longiflora Linn FArnidiol has anti-inflammatory activity, it
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Description Arnidiol is a pentacyclic triterpene isolated from Barleria Longiflora Linn FArnidiol has anti-inflammatory activity, it possesses marked inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice.
In vitro Fifteen pentacyclic triterpene diols and triols, consisting of six taraxastanes, faradiol (1), heliantriol B0 (2), heliantriol C (3), 22alpha-methoxyfaradiol (4), Arnidiol (5), and faradiol alpha-epoxide (6); five oleananes, maniladiol (7), erythrodiol (8), longispinogenin (9), coflodiol (10), and heliantriol A(1) (11); two ursanes, brein (12) and uvaol (13); and two lupanes, calenduladiol (14) and heliantriol B2 (15), isolated from the non-saponifiable lipid fraction of the edible flower extract of chrysanthemum (Chrysanthemum morifolium) were evaluated for their inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate, in Raji cells as a primary screening test for anti-tumor-promoters.
molecular weight 442.72
Molecular formula C30H50O2
CAS 6750-30-7
Storage Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility DMSO: 6 mg/mL (13.55 mM), Sonication is recommended.
References 1. Constituents of Compositae plants III. Anti-tumor promoting effects and cytotoxic activity against human cancer cell lines of triterpene diols and triols from edible chrysanthemum flowers.Cancer Lett., 2002, 177(1):7-12.