| Description | Isoschaftoside is used as an intercrop due to its allelopathic inhibition of parasitism by Striga hermonthica, an obligate parasitic weed that can devastate the maize crop. Isoschaftoside has anti-tumor, antioxidant, and antimicrobial activities, it also possesses strong nematicidal activity against M. incognita. |
| In vitro | 方法与结果：在东非小规模农户的玉米种植中，作为饲料的豆科植物Desmodium uncinatum因其对Striga hermonthica的化感抑制作用而被用作间作物。Striga hermonthica是一种会严重破坏玉米作物的必需寄生性杂草。通过对D. uncinatum根提取物的生物检测引导分离，发现Isoschaftoside是抑制已萌发的S. hermonthica根系生长的主要成分。使用来自不同植物源Passiflora incarnata的Isoschaftoside重复的生物检测证明了其为生物活性成分。结论：通过对水培D. uncinatum根系分泌物的分析，发现Isoschaftoside在水培介质中以10-100 nM的生物活性浓度存在。 |
| molecular weight | 564.49 |
| Molecular formula | C26H28O14 |
| CAS | 52012-29-0 |
| Storage | keep away from direct sunlight|Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (88.58 mM) |
| References | 1. Isoschaftoside, a C-glycosylflavonoid from Desmodium uncinatum root exudate, is an allelochemical against the development of Striga. Phytochemistry, 2010, 71(8-9):904-908. 2. Phenol content related to antioxidant and antimicrobial activities of Passiflora spp. extracts. European Food Research and Technology, 2006, 223(1):102-109. 3. Nematocidal Flavone-C-Glycosides against the Root-Knot Nematode (Meloidogyne incognita) from Arisaema erubescens Tubers. Molecules, 2011, 16(6):5079-5086. 4. Network Pharmacology-based Study of the Active Constituents of Chinese Medicinal Formulae for Antitumor Mechanism. World Journal of Traditional Chinese Medicine (English), 2018. |