| Description | 5-Geranoxy-7-methoxycoumarin shows antifungal activity. |
| In vitro | 柑橘类水果抵抗病原体的两种机制（预形成和诱导型抗真菌物质）进行了研究。方法与结果表明，柠檬的外层果皮组织含有以下预形成抗真菌物质：citral、limettin、5-Geranoxy-7-methoxycoumarin 与 isopimpinellin，它们构成了对抗病原体的第一道防线。外源性应用citral至接种Penicillium的柠檬果实可防止腐烂。当柑橘类水果受到真菌挑战和/或非生物胁迫时，会被诱导产生植物抗素scoparone，被认为是水果防御的另一线。根据抑制菌丝管伸长或孢子萌发的中位有效剂量（ED50），scoparone对Penicillium digitatum Sacc.的抗真菌毒性高于预形成抗真菌物质。不同柑橘类物种（柠檬、橙子、葡萄柚、青柠、金桔）在响应联合Penicillium接种和热处理或UV照射产生scoparone的能力上存在差异。UV照射柠檬果实降低了其对P. digitatum的易感性。结论：该效应的表达与受光照果实中scoparone的水平直接相关。高剂量的UV光和citral应用对外层果皮组织明显有害。 |
| molecular weight | 328.4 |
| Molecular formula | C20H24O4 |
| CAS | 7380-39-4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 3.28 mg/mL (10 mM) |
| References | 1. Preformed and induced antifungal materials of citrus fruits in relation to the enhancement of decay resistance by heat and ultraviolet treatments. Journal of Agricultural and Food Chemistry, 1992, 40(7):1217-1221. |
| Citations | 1. Li S, Kelly C, Knob R, et al.Analysis of Coumarin-Based Phototoxins in Citrus-Derived Essential Oils Using Liquid Chromatography-Mass Spectrometry.Chromatographia.2023: 1-11. |