| Description | Isoflurane (Forane) is a stable, non-explosive inhalation anesthetic that has been reported to induce caspase-3 activation. |
| Synonyms | HSDB-8057, Forane, HSDB 8057, 异氟醚, HSDB8057, Terrell |
| molecular weight | 184.49 |
| Molecular formula | C3H2ClF5O |
| CAS | 26675-46-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 60 mg/ml (325.22 mM) |
| References | 1. Olutoye OA, Sheikh F, Zamora IJ, Yu L, Akinkuotu AC, Adesina AM, Olutoye OO. Repeated isoflurane exposure and neuroapoptosis in the midgestation fetal sheep brain. Am J Obstet Gynecol. 2016 Apr;214(4):542.e1-8. doi: 10.1016/j.ajog.2015.10.927. Epub 2015 Nov 4. PubMed PMID: 26546852. 2. Chang PS, Walker SM, Fitzgerald M. Differential Suppression of Spontaneous and Noxious-evoked Somatosensory Cortical Activity by Isoflurane in the Neonatal Rat. Anesthesiology. 2016 Apr;124(4):885-98. doi: 10.1097/ALN.0000000000001017. PubMed PMID: 26808637. |
| Citations | 1. Fan P, Wang Y, Li J, et al. lncRNA PAPPA-AS1 Induces the Development of Hypertrophic Scar by Upregulating TLR4 through Interacting with TAF15. Mediators of Inflammation. 2021, 2021. 2. Chen X, Yun C, Zheng H, et al. The protective effects of S14G-humanin (HNG) against streptozotocin (STZ)-induced cardiac dysfunction. Bioengineered. 2021, 12(1): 5491-5503. 3. Pang J, Zhu L, Lv Y, et al.miR-15a-5p up-regulates TLR4 and induces the formation of hypertrophic scars and keloids.Cellular and Molecular Biology.2023, 69(7): 158-163. |