| Description | IRAK4-IN-25 (compound 38), a potent oral IRAK4 inhibitor (IC50 = 7.3 nM) with low clearance (Cl = 12 mL/min/kg), effectively suppresses pro-inflammatory cytokine production and demonstrates favorable in vitro safety and ADME profiles. It is suitable for research on inflammatory and autoimmune disorders [1]. |
| molecular weight | 435.48 |
| Molecular formula | C23H25N5O4 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |