| Description | IRAK4-IN-10 is a potent IRAK4 inhibitor (IC50: 1.5 nM) with potential anticancer and anti-inflammatory activities.IRAK4-IN-10 blocks MyD88 signaling and can be used for the study of autoimmune diseases and cancers. |
| Target activity | IRAK4:1.5 nM |
| molecular weight | 400.48 |
| Molecular formula | C22H24N8 |
| CAS | 2681278-09-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Sabnis RW. Novel Tricyclic Heteroaryl Compounds as IRAK4 Inhibitors for Treating Cancer, Autoimmune and Inflammatory Diseases. ACS Med Chem Lett. 2022 Feb 28;13(3):336-337. |