| Description | IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM). |
| In vitro | IRAK-4 protein kinase inhibitor 2 同时也抑制了 IRAK-1（IC50 <10 μM）[1]。 |
| Target activity | IRAK1:4 μM |
| molecular weight | 282.25 |
| Molecular formula | C14H10N4O3 |
| CAS | 301675-24-1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: ＜1 mg/mL (insoluble or slightly soluble) |
| References | 1. Powers JP, et, al. Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4. Bioorg Med Chem Lett. 2006 Jun 1;16(11):2842-5. |
IRAK-4 protein kinase inhibitor 2
CAS No.: 301675-24-1
IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM
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