| Description | IMB-301 is a small molecular inhibitor via virtual screening according to the hA3G model. |
| In vitro | IMB-301 binds to hA3G that interrupts the hA3G-Vif interaction and inhibits Vif-mediated degradation of hA3G. |
| molecular weight | 379.26 |
| Molecular formula | C19H17Cl2FN2O |
| CAS | 64009-84-3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 90 mg/mL (237.3 mM), Sonication is recommended. |
| References | 1. Ma L, et al. Identification of small molecule compounds targeting the interaction of HIV-1 Vif and human APOBEC3G by virtual screening and biological evaluation. Sci Rep. 2018;8(1):8067. Published 2018 May 23. |