| Description | CGRP antagonist 1 is a potent CGRP receptor antagonist with Ki values of 35 nM and IC50 values of 57 nM, respectively.CGRP antagonist 1 can be used for the study of cardiovascular and neurovascular diseases. |
| Target activity | CGRP receptor:35 nM（Ki）, CGRP receptor:57 nM |
| molecular weight | 494.54 |
| Molecular formula | C29H26N4O4 |
| CAS | 1123757-49-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 60 mg/mL (121.32 mM) |
| References | 1. Stump CA, et al. The discovery of highly potent CGRP receptor antagonists. Bioorg Med Chem Lett. 2009 Jan 1;19(1):214-7. |