Description | IL-17 modulator 4 is a prodrug of IL-17 modulator 1 which is an efficacious modulator of IL-17. |
molecular weight | 474.6 |
Molecular formula | C27H34N6O2 |
CAS | 2446803-65-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility | DMSO: 270 mg/mL (568.9 mM), Sonication is recommended. |
References | 1. Kevin Neil Dack, et al. Amino-acid anilides as small molecule modulators of il-17. WO2020127685A1. 2. Andrews MD, et al. Discovery of an Oral, Rule of 5 Compliant, Interleukin 17A Protein-Protein Interaction Modulator for the Potential Treatment of Psoriasis and Other Inflammatory Diseases. J Med Chem. 2022 Jul 14;65(13):8828-8842. |