| Description | ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy |
| Target activity | KCNQ1:15 μM, KCNQ2/Q3:0.38 μM(EC50) |
| molecular weight | 267.11 |
| Molecular formula | C12H8Cl2N2O |
| CAS | 325457-99-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 14 mg/mL (52.41 mM) |
| References | 1. Amato G , Roeloffs R , Rigdon G C , et al. N-Pyridyl and Pyrimidine Benzamides as KCNQ2/Q3 Potassium Channel Openers for the Treatment of Epilepsy[J]. ACS Medicinal Chemistry Letters, 2011, 2(6):481. |