| Description | Hydroxyethyl cellulose (2-Hydroxyethyl cellulose) is a nonionic water-soluble modified cellulose polymer used as a thickener in water-soluble cosmetics and personal care formulations. |
| In vitro | Hydroxyethyl cellulose在LDH的冻融过程中显示出卓越的低温保护效果，在冻干过程中具有显著的干燥保护效果。退火对Hydroxyethyl cellulose的稳定作用影响有限。通过在冻干前将表面活性剂Tween 80加入配方中，可以显著提高Hydroxyethyl cellulose裂解物的重构时间。使用Hydroxyethyl cellulose稳定生理溶液中的氧化石墨烯，使得结果纳米复合物适用于靶向药物输送。Hydroxyethyl cellulose在电解质溶液中有效稳定氧化石墨烯，其稳定机制似乎依赖于Hydroxyethyl cellulose的含量。纳米复合物中的Hydroxyethyl cellulose含量在其作为可控药物释放载体或作为叶酸靶向药物载体的最终应用中发挥重要作用。 |
| Synonyms | Cellulose hydroxyethyl ether, 羟乙基纤维素, 2-Hydroxyethyl cellulose |
| molecular weight | N/A |
| CAS | 9004-62-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | H2O: 9.09 mg/mL, Heating to 93℃ is recommended. DMSO: 1 mg/mL (insoluble or slightly soluble) |
| References | 1. Mianehrow H, et al. Graphene-oxide stabilization in electrolyte solutions using hydroxyethyl cellulose for drug delivery application. Int J Pharm. 2015 Apr 30;484(1-2):276-82. 2. Al-Hussein A, et al. Investigation of the stabilizing effects of hydroxyethyl cellulose on LDH during freeze drying and freeze thawing cycles. Pharm Dev Technol. 2015 Jan;20(1):50-9. |