| Description | GSK2981278 (ROR gama modulator 1) is a highly potent and selective inverse agonist of retinoic acid receptor-related orphan receptor gamma (ROR gamma). |
| Synonyms | ROR gama modulator 1 |
| molecular weight | 461.61 |
| Molecular formula | C25H35NO5S |
| CAS | 1474110-21-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 50 mg/mL (108.31 mM) |
| References | 1. Birault Veronique, et al. Preparation of tetrahydropyranylmethoxy benzenesulfonamide compounds as RORγ modulators useful in therapy of various diseases. From PCT Int. Appl. (2015), WO 2015061515 A1 20150430. 2. Birault Veronique, et al. Preparation of tertiary N-arylbenzenesulfonamides as RORγ modulators useful in treatment of inflammatory, metabolic, and autoimmune diseases. From PCT Int. Appl. (2013), WO 2013160418 A1 20131031. |