| Description | Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7 µM[1][2]. |
| Synonyms | NSC 329491, NSC329491, NSC-329491 |
| molecular weight | 244.2 |
| Molecular formula | C13H8O5 |
| CAS | 529-49-7 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 22.5 mg/mL (92.14 mM) |
| References | 1. Wang H, et al. Identification and determination of four metabolites of mangiferin in rat urine. J Pharm Biomed Anal. 2007;45(5):793-798. 2. Tzankova, Virginia et al. (2010). Inhibition of 5-HT uptake by some constituents of Hypericum annulatum in rat brain in vitro. Pharmacologyonline. 2. 3. Na Z, Xu Y. [Chemical constituents from twigs of Garcinia xipshuanbannaensis]. Zhongguo Zhong Yao Za Zhi. 2009 Sep;34(18):2338-42. Chinese. PubMed PMID: 20030083. 4. Mkounga P, Fomum ZT, Meyer M, Bodo B, Nkengfack AE. Globulixanthone F, a new polyoxygenated xanthone with an isoprenoid group and two antimicrobial biflavonoids from the stem bark of Symphonia globulifera. Nat Prod Commun. 2009 Jun;4(6):803-8. PubMed PMID: 19634326. |