| Description | Gadoxetate Disodium is used to evaluate focal liver lesions, such as hepatocellular carcinoma or liver metastasis on T1-weighted imaging. It is a contrast agent in magnetic resonance imaging (MRI) of the hepatobiliary system. It accumulates in normal, functioning hepatocytes. |
| Synonyms | Gd-EOB-DTPA Disodium, 钆塞酸二钠, ZK 139834 |
| molecular weight | 725.71 |
| Molecular formula | C23H28GdN3Na2O11 |
| CAS | 135326-22-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 7.03 mg/mL (10 mM) |
| References | 1. Schuhmann-Giampieri G, et al. Preclinical evaluation of Gd-EOB-DTPA as a contrast agent in MR imaging of the hepatobiliary system. Radiology. 1992 Apr;183(1):59-64. 2. Katsube T, et al. Estimation of liver function using T1 mapping on Gd-EOB-DTPA-enhanced magnetic resonance imaging. Invest Radiol. 2011 Apr;46(4):277-83. 3. Saito K, et al. Gd-EOB-DTPA enhanced MRI for hepatocellular carcinoma: quantitative evaluation of tumor enhancement in hepatobiliary phase. Magn Reson Med Sci. 2005;4(1):1-9. |