| Description | D-Fructose-1,6-bisphosphate sodium salt hydrate is the intermediate in carbohydrate metabolism, including glycolysis and gluconeogenesis. During glycolysis, it is produced by phosphorylation of fructose-6-phosphate by phosphofructokinase. The reverse reaction mediated by fructose-1, 6-diphosphatase-1 is one of the rate-limiting steps of gluconeogenesis. The same reaction occurs in the chloroplasts of plants, D-Fructose-1,6-bisphosphate sodium salt hydrate as part of the reducing pentose phosphate cycle. Since cancer cells use glycolysis as a primary source of metabolic energy production, this pathway has become a major target for cancer chemotherapy. |
| Synonyms | D-Fructose-1,6-bisphosphate , sodium salt, hydrate (1:3:8) |
| molecular weight | 550.18 |
| Molecular formula | C6H27Na3O20P2 |
| CAS | 81028-91-3 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: < 1 mg/mL (insoluble） PBS (pH 7.2): 10 mg/mL |
| References | 1. Wang DS, et al. Establishment and evaluation of a rabbit model of arterial thrombosis by collagen encapsulated thread-drawing. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2008;33(11):993-998. |
Fosfructose, sodium salt, hydrate (1:3:8)
CAS No.: 81028-91-3
D-Fructose-1,6-bisphosphate sodium salt hydrate is the intermediate in carbohydrate metabolism, including glycolysis and
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