| Description | Fibrinopeptide A, human acetate (Human fibrinopeptide A acetate) is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A (FPA) is produced from the N-terminal Aα region of fibrinogen protein, on cleavage by thrombin. |
| In vitro | 单体纤维蛋白原向聚合体纤维蛋白的转化由凝血酶介导，该酶结合于纤维蛋白原的中心区域并催化切割位于Aα和Bβ链NH2-末端的2个短肽，即16残基的纤维蛋白肽A (FpA) 和14残基的纤维蛋白肽B (FpB)[1]。 |
| In vivo | Fibrinopeptide A(FPA)是一种由凝血酶从纤维蛋白原中切割出的小分子多肽，具有短半衰期，并被认为是凝血酶活性、纤维蛋白生成和持续血栓形成的敏感生化标志物[2]。 |
| Synonyms | Fibrinopeptide A, human acetate(25422-31-5 free base), Human fibrinopeptide A acetate |
| molecular weight | 1596.65 |
| Molecular formula | C65H101N19O28 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 5 mM |
| References | 1. Riedel T, et al. Fibrinopeptides A and B release in the process of surface fibrin formation. Blood. 2011 Feb 3;117(5):1700-6. |