| Description | Feralolide, a dihydroisocoumarin from the methanolic extract of aloe vera resin, functions as a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), with IC50 values of 55 μg/mL and 52 μg/mL, respectively. It exhibits antioxidant properties, effectively inhibiting 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS). Research suggests feralolide's potential in studying cognitive disorders, including Alzheimer's disease, for its memory restoration and enhancement capabilities [1]. |
| molecular weight | 344.32 |
| Molecular formula | C18H16O7 |
| CAS | 149418-38-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |