| Description | Aloenin aglycone (compound 13), an inhibitor of NF-κB, can be sourced from aloe exudate. It impedes TNFα-stimulated NF-κB transcriptional activity, showing an IC 50 of 18.7 μM. At a concentration of 10 μM, aloenin aglycone decreases both inducible nitric oxide synthase (iNOS) and intercellular adhesion molecule 1 (ICAM-1) gene expression in HepG2 cells exposed to 10 ng/mL TNFα [1]. |
| molecular weight | 248.23 |
| Molecular formula | C13H12O5 |
| CAS | 59163-53-0 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |