| Description | Fasentin (N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide) is an inhibitor of GluT1. |
| In vitro | Fasentin 被描述为 GLUT-1 和 GLUT-4 运输体的调节剂，因此在某些癌细胞中抑制了葡萄糖的摄取。 |
| Target activity | GLUT4:68 μM (IC50) |
| Synonyms | N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide |
| molecular weight | 279.64 |
| Molecular formula | C11H9ClF3NO2 |
| CAS | 392721-37-8 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 25 mg/mL (89.4 mM) |
| References | 1. Ocaa M C , Beatriz Martínez-Poveda, Manuel Marí-Beffa, et al. Fasentin diminishes endothelial cell proliferation, differentiation and invasion in a glucose metabolism-independent manner[J]. entific Reports, 2020, 10(1). 2. Kraus, Dominik, Reckenbeil, et al. Targeting glucose transport and the NAD pathway in tumor cells with STF-31: a re-evaluation[J]. Cellular Oncology, 2018. |