| Description | Ethacridine lactate (Acrinol) is a poly(ADP-ribose) glycohydrolase (PARG) inhibitor. |
| In vitro | Ethacridine lactate 是一种安全的妊娠终止药物，成功率大约为80%，几乎没有任何副作用[1]。 |
| Synonyms | 乳酸依沙吖啶, Acrinol, 6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE |
| molecular weight | 343.38 |
| Molecular formula | C18H21N3O4 |
| CAS | 1837-57-6 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 100 mg/mL (291.22 mM) |
| References | 1. Purandare V N , Mhatre V , Krishna U R , et al. The place of ethacridine lactate for mid-trimester M.T.P. (Multicentric study)[J]. Journal of Postgraduate Medicine, 1977, 23(2):77-83. 2. Gupta S , Sachdeva L , Gupta R . Ethacridine lactate -- a safe and effective drug for termination of pregnancy.[J]. INDIAN JOURNAL OF MATERNAL AND CHILD HEALTH, 1993, 4(2):59-61. |
| Citations | 1. Huang C Y, Nicholson M W, Wang J Y, et al. Population-based high-throughput toxicity screen of human iPSC-derived cardiomyocytes and neurons. Cell Reports. 2022, 39(1): 110643 |