| Description | EN106, a potent FEM1B inhibitor and a cysteine-reactive covalent ligand, effectively disrupts the recognition of FEM1B's crucial reductive stress substrate, FNIP1. |
| Synonyms | ZINC3888023 |
| molecular weight | 280.71 |
| Molecular formula | C13H13ClN2O3 |
| CAS | 757192-67-9 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility | DMSO: 200 mg/mL (712.5 mM), Sonication is recommended. |
| References | 1. Henning NJ, et al. Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications. J Am Chem Soc. 2022;144(2):701-708. |