| Description | Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities. |
| In vitro | Eleutheroside B1 可能影响 N-glycan 生物合成、趋化因子信号通路、细胞因子-细胞因子受体相互作用，特别是可能针对 POLR2A 来抑制流感病毒基因的生产。 |
| Synonyms | 刺五加苷B1 |
| molecular weight | 384.33 |
| Molecular formula | C17H20O10 |
| CAS | 16845-16-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 75 mg/ml (195.14 mM) |
| References | 1. Wen, Yan, Chunge, et al. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation.[J]. International Journal of Molecular Medicine, 2018. |