| Description | Eledoisin Related Peptide 2TFA (Eledoisin Related Peptide 2TFA (2990-43-4(free base))) is a tachykinin receptor ligand. |
| In vivo | Substance P和eledoisin-related peptide对呼吸神经元和反射神经元表现出兴奋作用，但与谷氨酸引起的效应相比，其激发作用起始较慢并且持续时间更长。这两种化合物既可以促进周期性活动，也能增强诱发活动，其效果的大小与喷射电流的幅度直接相关。研究表明，谷氨酸和Substance P（及其类似物eledoisin-related peptide）均能对呼吸神经元和反射神经元的活动产生兴奋效果[1]。 |
| Synonyms | Eledoisin Related Peptide 2TFA(2990-43-4(free base)) |
| molecular weight | 934.99 |
| Molecular formula | C38H60F6N8O10S |
| Storage | keep away from moisture|Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility | DMSO: 10 mM |
| References | 1. Henry J L , Sessle B J . Effects of glutamate, substance P and eledoisin-related peptide on solitary tract neurones involved in respiration and respiratory reflexes[J]. Neuroscience, 1985, 14(3):863-873. 2. Guyenet P G , Aghajanian G K . Excitation of neurons in the nucleus locus coeruleus by substance P and related peptides[J]. Brain Research, 1977, 136(1):178-184. |