| Description | EGLU ((2S)-α-Ethylglutamic acid) is a competitive mGluR-2 receptor antagonist with antidepressant activity and anti-injury effects, which can be used in the study of arthritis. |
| In vitro | EGLU（200 μM）选择性拮抗 -ACPD 诱导的 DRVRP 单突触成分抑制。[1] |
| Target activity | mGluR2:66 μM (Kd) |
| Synonyms | (2S)-α-Ethylglutamic acid, (2S)-α-EGLU |
| molecular weight | 175.18 |
| Molecular formula | C7H13NO4 |
| CAS | 170984-72-2 |
| Storage | |Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| References | 1. Jane DE, et al. Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord.Neuropharmacology. 1996;35(8):1029-35. |